Bipolar Affective Puerperal Psychosis: Genome-Wide Significant Evidence for Linkage to Chromosome 16
نویسندگان
چکیده
منابع مشابه
Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16.
OBJECTIVE Vulnerability to the triggering of bipolar episodes by childbirth aggregates in families and may define a genetically relevant subtype of bipolar disorder. The authors conducted a search by systematic whole genome linkage scan for loci influencing vulnerability to bipolar affective puerperal psychosis. METHOD The authors selected families with bipolar disorder from their previous bi...
متن کاملObstetric variables associated with bipolar affective puerperal psychosis.
BACKGROUND Previous cross-sectional studies have highlighted a number of obstetric variables that may be associated with the development of broadly defined puerperal (post-partum) psychosis. These include: (a) primiparity, (b) pregnancy complications, (c) delivery complications, (d) Caesarean section, (e) female baby and (f) shorter gestation period. AIMS To examine these risk factors in wome...
متن کاملRisk of puerperal and non-puerperal recurrence of illness following bipolar affective puerperal (post-partum) psychosis.
The clinical value of information on the risk of future psychiatric illness in women who have experienced puerperal (post-partum) psychosis has been limited by inconsistencies in terminology and nosology. Here we report rates of subsequent puerperal and non-puerperal episodes, in a well characterised sample of women diagnosed with clearly defined bipolar affective puerperal psychosis (n=103). O...
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BACKGROUND Maintenance of high muscular fitness is positively related to bone health, functionality in daily life and increasing insulin sensitivity, and negatively related to falls and fractures, morbidity and mortality. Heritability of muscle strength phenotypes ranges between 31% and 95%, but little is known about the identity of the genes underlying this complex trait. As a first attempt, t...
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Hypertension was one of the first complex traits to be studied and is thought to be influenced by polygenic and multiple environmental risk factors. Several genomic studies have found suggestive logarithm of odds (LOD) scores for either blood pressure or essential hypertension, but few loci have been replicated. In this study, we performed a genome-wide linkage analysis for systolic blood press...
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ژورنال
عنوان ژورنال: American Journal of Psychiatry
سال: 2007
ISSN: 0002-953X,1535-7228
DOI: 10.1176/ajp.2007.164.7.1099